Selective Dimerization of Aryl-substituted Terminal Alkynes on Bis(indenyl)zirconocene Derivatives
نویسندگان
چکیده
منابع مشابه
Rhodium-catalyzed (E)-selective cross-dimerization of terminal alkynes.
Cross-dimerization of various terminal alkynes with different bulky terminal alkynes such as triisopropylsilylacetylene and 1-trimethylsilyloxy-1,1-diphenyl-2-propyne efficiently proceeds in the presence of a rhodium catalyst system to produce the corresponding (E)-enynes with high regio- and stereoselectivity.
متن کاملLigand mediated iron catalyzed dimerization of terminal aryl alkynes: scope and limitations.
Regioselective dimerization of terminal aryl alkynes to produce conjugated enynes has been achieved using FeCl3 and KO(t)Bu in the presence of either DMEDA or dppe. The reaction proceeds smoothly in toluene at 145 °C for 2 h to give the corresponding head-to-head dimers in good to excellent yields (54 to 99%) with high E-selectivity (67 : 33 to 83 : 17 E/Z). Both strongly electron-donating and ...
متن کاملPreparation of substituted enol derivatives from terminal alkynes and their synthetic utility.
Stereodefined enol derivatives of aldehydes are prepared from terminal alkynes. Specifically, terminal alkynes are known to undergo Cp2ZrCl2-catalyzed methylalumination. Here, we show that the resultant vinylalanes can be oxygenated with peroxyzinc species to generate trisubstituted enolates. Electrophilic trapping with carboxylic anydrides or silyl triflates yields trisubstituted enol esters o...
متن کاملHighly selective synthesis of tetra-substituted furans and cyclopropenes: copper(I)-catalyzed formal cycloadditions of internal aryl alkynes and diazoacetates.
A convenient Cu(I)-catalyzed cycloaddition of electron rich internal aryl alkynes and diazoacetates was discovered for the chemoselective and regioselective synthesis of tetra-substituted furans and cyclopropenes in moderate isolated yields (18-67%), and alkyne conversion (29-73%).
متن کاملIndium(III) catalysed substrate selective hydrothiolation of terminal alkynes.
In(OTf)(3) is reported as the first catalyst having the ability to selectively catalyse both Markovnikov and anti-Markovnikov hydrothiolation of terminal alkynes under identical reaction conditions depending upon the nature of the thiol employed.
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ژورنال
عنوان ژورنال: Chemistry Letters
سال: 2011
ISSN: 0366-7022,1348-0715
DOI: 10.1246/cl.2011.1443